TABLE 1.Intrinsic membrane properties of chandelier and basket fast spiking neurons in layers 2/3 of monkey DLPFC
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Chandelier Cells | Basket Cells | |
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n | 12 | 16 |
Resting membrane potential, mV | –66.6 ± 1.0 | –67.6 ± 1.2 |
Input resistance, MΩ | 184 ± 22 | 179 ± 13 |
Time constant (ms) | 10.7 ± 1.1 | 9.5 ± 0.8 |
AHP amplitude, mV | 28.4 ± 1.6 | 30.9 ± 2.0 |
Spike width at half amplitude, ms | 0.35 ± 0.02 | 0.37 ± 0.01 |
Spike width at base, ms | 0.84 ± 0.06 | 0.76 ± 0.09 |
Spike amplitude, mV | 78.7 ± 2.1 | 75.3 ± 2.7 |
Spike V threshold, mV | –39.6 ± 2.2 | –36.6 ± 6.7 |
Spike I threshold, pA | 100 ± 14 | 160 ± 23* |
ISI ratio | 1.10 ± 0.04 | 1.09 ± 0.05 |
Data are shown as means ± SE. DLPFC, dorsolateral prefrontal cortex; AHP, afterhyperpolarization; spike V threshold, voltage
threshold for spiking; spike I threshold, current threshold for spiking; ISI ratio: ratio between last and first interspike
interval.
* , statistically significant difference between means, P < 0.05. Student's t-test.